The algorithm outperformed six radiologists in reading mammograms
AI was still as good as two doctors working together.
Unlike humans, AI is tireless. Experts say it could improve detection.
The current system in the NHS uses two radiologists to analyse each woman's X-rays. In rare cases where they disagree, a third doctor assesses the images.
In the research study, an AI model was given anonymised images, so that the women could not be identified.
Unlike the human experts, who had access to the patient's history, AI had only the mammograms to go on.
The results showed that the AI model was as good as the current double-reading system of two doctors.
And it was actually superior at spotting cancer than a single doctor.
Compared to one radiologist, there was a reduction of 1.2% in false positives, when a mammogram is incorrectly diagnosed as abnormal.
There was also a reduction of 2.7% in false negatives, where a cancer is missed.
Dominic King from Google Health said: "Our team is really proud of these research findings, which suggest that we are on our way to developing a tool that can help clinicians spot breast cancer with greater accuracy."
Most of the mammograms came from Cancer Research UK's OPTIMAM dataset collected from St George's Hospital London, the Jarvis Breast Centre in Guildford and Addenbrooke's Hospital, Cambridge.
It takes over a decade of training as a doctor and specialist to become a radiologist, capable of interpreting mammograms.
Reading X-rays is vital but time-consuming work, and there is an estimated shortage of more than 1,000 radiologists across the UK.
AI was as accurate as two doctors working together
No. It took humans to design and train the artificial intelligence model.
This was a research study, and as yet the AI system has not been let loose in the clinic.
Even when it is, at least one radiologist would remain in charge of diagnosis.
But AI could largely do away with the need for dual reading of mammograms by two doctors, easing pressure on their workload, say researchers.
Prof Ara Darzi, report co-author and director of the Cancer Research UK (CRUK) Imperial Centre, told the BBC: "This went far beyond my expectations. It will have a significant impact on improving the quality of reporting, and also free up radiologists to do even more important things."
Women aged between 50 and 70 are invited for NHS breast screening every three years - those who are older can ask to be screened.
The use of AI could eventually speed up diagnosis, as images can be analysed within seconds by the computer algorithm.
Sara Hiom, director of cancer intelligence and early diagnosis at CRUK, told the BBC: "This is promising early research which suggests that in future it may be possible to make screening more accurate and efficient, which means less waiting and worrying for patients, and better outcomes."